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Check out this week's newsletter from the Emerging Scholar Podcast: https://lnkd.in/e8aRWUmy  Released last week in JAMA- JAMA Pediatrics: https://lnkd.in/exDSBnAP As part of our on-going JDRF/FRDJ Canada / CIHR Institute of Population and Public Health (IPPH) funded trial of peer mentoring and type 1 diabetes (www.teamtrial.ca), we asked two simple questions about automated insulin devices and adolescent health outcomes: How well do they work in the real world, for prolonged periods for teens and are they improving their quality of life? Surprising we found little quality evidence to guide the answer. In partnership with young adult mentors living with T1D and patient partners from Diabetes Action Canada | CIHR SPOR Network, we launched into a systematic review and meta-analysis of RCTs comparing AIDs to all forms of diabetes management. What did we find? Among 902 youth with T1D (n=11 trials) followed for, on average, 31 weeks: (1) AIDs dramatically improve time in range for youth with T1D by a whopping 11%!, This is coupled with a modest 0.4% improvement in A1c. (2) The gains in time in range are driven largely by reducing time in hyperglycemia, and these effects are driven almost entirely during the night time. (3) There is a glaring absence of studies that inclde health outcomes relevant to teen and families living with T1D. So alot of room for more research in this area. We are grateful to everyone that contributed and our on going support from DREAM Trainees Children's Hospital Research Institute of Manitoba University of Manitoba Rady Faculty of Health Sciences, University of Manitoba JDRF/FRDJ Canada  |
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September 2025
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